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ME-Fab® Platform

The foundation: additive manufacturing of patient-matched implants.

ME-Fab® is the production engine behind Excellent MedTech's flagship products. It combines patient CT/MRI data, biomimetic design, and Electron Beam Melting of Ti-6Al-4V ELI to produce Class III implants with sub-millimetre anatomical match and gradient-optimised porous micro-architecture.

Technical Highlights

Bionic match. Gradient structure. Validated performance.

Biomimicry

95%+ bionic match

30,000+ real-sample deep-learning models reconstruct cranial curvature 1:1 from CT/MRI. Sub-millimetre matching accuracy on first placement.

Mechanical

1,400 N compressive strength

Anti-impact deformation < 0.7 mm. Fatigue resistance ≥ 5 million cycles. Verified under simulated normal surgical fixation conditions.

Biological

Native TiO₂ osseointegration

Medical Ti-6Al-4V ELI forms bionic interfaces with hard and soft tissue via Ti-OH and Ti-O-R covalent bonds.

The Process

Why Electron Beam Melting, not SLM?

For titanium medical implants, EBM is preferred over Selective Laser Melting (SLM) because of three reasons: lower oxygen pickup (vacuum environment), lower residual stress (700 °C built-in pre-heat), and higher build rate (commercially viable for one-off patient implants).

Heat source60 kV / 3–30 mA electron beam
Build environmentVacuum < 1×10⁻³ mbar
Pre-heat700 °C (built-in)
Layer thickness50–100 µm
Oxygen in chamber< 50 ppm
Residual stressLower vs. SLM

EBM vs. SLM — at a glance

AttributeEBM (ours)SLM / DMLS
Heat sourceElectron beamFibre laser
Build environmentVacuumInert gas (Ar / N₂)
Pre-heat700 °CNone / mild
Residual stressLowerHigher
Oxygen pickupVery lowHigher
Build rateHigherLower
Micro-Architecture

Gradient porous. The four numbers that matter.

Every porous titanium implant is defined by four numbers. Our values sit inside the windows proven to support bone ingrowth while preserving mechanical integrity.

ParameterOur specRationale
Porosity (bone-contact)60 – 80%Mirrors cancellous bone
Porosity (load-bearing)20 – 40%Maintains bulk strength
Pore size300 – 800 µm"Bobyn window" — supports osteoblast ingrowth
Strut thickness200 – 500 µmBalances adhesion vs. buckling
Interconnectivity window≥ 100 µm"Klawitter-Hulbert threshold"

References: Bobyn et al. Clin Orthop 1980; Klawitter & Hulbert J Biomed Mater Res Symp 1971.

CROSS-SECTION · GRADIENT POROUS Bone-contact zone Transition zone Load-bearing zone Density →      Porosity ↑      Pore size ↑
Mechanical Performance

Validated against the most demanding standards.

Test Method / Standard Our result Titanium mesh PEEK plate
Quasi-static compressive failure ASTM F382 1,400 N peak ~40 N ~40 N (loosening)
Impact deformation Internal drop rig < 0.7 mm max, full elastic recovery > 7 mm permanent indent Fractures
Fatigue ASTM F382 / ISO 14801 ≥ 5 × 10⁶ cycles < 1 × 10⁶ < 5 × 10⁵
Tensile strength ASTM E8 ≥ 860 MPa UTS, ≥ 795 MPa YS
Elongation ASTM E8 ≥ 10%
Density (after HIP) Archimedes + image analysis ≥ 99.5%
FEA Acceptance Criteria

Every design is FEA-validated before manufacture.

We run patient-specific FEA before manufacturing. A design is only released for build when all three criteria are satisfied.

Peak von Mises stress

< 440 MPa — < half of Ti-6Al-4V ELI yield strength (880 MPa). Provides infinite-life fatigue margin.

Interfacial micromotion

< 50 µm — Pilliar threshold. Below this, bone ingrows; above, fibrous tissue forms.

Stress-shielding ratio

0.7 – 1.3 — implant strain ÷ bone strain. Too low → resorption; too high → overload.

Material Specification

Medical-grade Ti-6Al-4V ELI. Engineered for the body.

Item Specification Standard
PowderTi-6Al-4V ELI, gas-atomised, sphericalASTM F136, ASTM F3301 (powder)
Particle size distribution45 – 105 µmASTM B214, ISO 13322-1
Oxygen in finished part< 2,000 ppmASTM F136 / ISO 5832-3
Surface roughness (post-EBM)Ra 5 – 15 µm (as-built)ISO 4287/4288
Post-processingStress relief (730 °C / 2 h / vacuum) or HIP (900–950 °C / 100 MPa / 4 h / Ar)ASTM F3301
Final cleaningUltrasonic + passivationASTM F86
SterilisationEO (default) or gammaISO 11135 / 11137
PackagingDouble-pouch + Tyvek, ISO Class 7ISO 11607-1/-2

See ME-Fab® in action.

Explore the flagship product of the ME-Fab® platform — our Class III patient-matched skull reconstruction system.

Skull Reconstruction System All Platforms