NMPA Class III — 国械注准 20263130176

Additive Manufacturing Patient-Matched Skull Reconstruction System

The world's first patient-matched Class III cranial implant validated by a large-cohort prospective clinical study. Sub-millimetre anatomical match, gradient porous micro-architecture, < 2% total complication rate.

ModelsDLZ04 · DLZ05
Size range30 – 200 mm
MaterialTi-6Al-4V ELI
Screw materialTC4 titanium
ProcessElectron Beam Melting
ClassClass III (NMPA)
Cert. No.国械注准 20263130176
Lead time5–7 working days
The Five Differentiation Pillars

Why surgeons choose the Skull Reconstruction System.

Pillar 1

Perfect anatomical match

Every cranial defect is unique. Off-the-shelf titanium mesh and PEEK plates force the surgeon to manually bend, cut, and trim. Our implant is reverse-engineered from the patient's own CT/MRI — sub-millimetre accuracy on first placement.

Pillar 2

Outstanding biocompatibility

Native TiO₂ oxide layer carries Ti-OH groups that bind protein hydroxyl side-chains through hydrogen bonds and Ti-O-R covalent bonds. The molecular basis for titanium's long-term in-vivo stability.

Pillar 3

Operability / surgical efficiency

Medicine-Engineering Interaction (MEI) — the surgeon and our medical engineer sign off on the design before the patient is on the table. No "discovering" geometry intra-operatively.

Pillar 4

Natural aesthetic outcome

1:1 cranial curvature restoration with smooth transition curves and midline symmetry. Post-op facial symmetry, self-confidence, and quality-of-life metrics recover together.

Pillar 5

Clinical evidence — < 2% complications

The first PSI CMF implant validated by a large-cohort prospective clinical study. Total complication rate < 2% vs. 12–18% for conventional mesh / PEEK.

Pillar 6

CT & MRI compatibility

Multi-applicable, multi-modal imaging: porous design reduces CT artifacts. MRI-safe (non-magnetic, mild and safe heat). Clear post-op imaging enables easy follow-up.

Mechanical Performance

One-of-a-kind. Literally.

These mechanical performance numbers are not just better than mesh and PEEK — they are at the upper boundary of what biomimetic engineering can achieve for cranial reconstruction.

ASTM F382
1,400 N

Compressive failure strength

vs. ~40 N for titanium mesh and PEEK

Impact
< 0.7 mm

Max deformation, full elastic recovery

vs. > 7 mm permanent indent for mesh

ISO 14801
5×10⁶

Fatigue cycles to failure

vs. < 10⁶ for mesh; < 5×10⁵ for PEEK

How the Skull Reconstruction System Compares

The numbers that change the conversation.

Endpoint Excellent MedTech 3D PSI Titanium mesh PEEK plate
Total complication rate< 2%12.2 – 17.4%17.2 – 18.5%
Infection< 1.7%6.05 – 8.2%5.1 – 8.8%
Re-operation (critical failure)None observed3.70%8.60%
Subcutaneous effusionNone observed9.1 – 18.9%28.6 – 33%
Implant exposureNone observed2.1 – 5.8%0.8 – 2.2%
Chronic headache / foreign-body painNone observed12 – 18.5%5.0 – 7.1%
Loosening / migrationNone observed1.1 – 3.8%1.0 – 3.1%
CT artifactsReduced by porous designPresent, acceptableNone, but blurry
MRI safetySafe, mild heatSafe, mild heatSafe, no heat

Source: large-cohort prospective clinical study (5,000+ cases) vs. peer-reviewed literature controls.

Order workflow

From CT to sterile implant in 5–7 working days.

1

Send CT

DICOM upload + defect description

2

Design

Image recon · biomimetic design · FEA

3

MEI sign-off

Surgeon-engineer review

4

Manufacture

EBM build · post-process · inspect

5

Deliver

Sterile pack · DHL/FedEx

What surgeons say

Tested in 50+ clinical partner sites.

Our clinical partners include the Fourth Military Medical University, Southern Medical University affiliated hospitals, Shenzhen Second People's Hospital, Beijing Tiantan, Huashan, Xuanwu, and 500+ other sites across China.

"The MEI workflow changes the surgical experience. By the time the patient is on the table, the geometry is no longer a surprise — it's an execution."

— Senior neurosurgeon, Class III academic hospital, China

"For large bifrontal defects, the patient-matched geometry with porous bone-contact surface is the difference between a 90-minute surgery and a 3-hour surgery."

— Chief of neurosurgery, southern medical university affiliated hospital

Start a patient case.

Our team responds to clinical intake within 24 hours. Hospital distributors, send your surgeon to the form. Direct inquiries welcome.

Request a Quote Specifications